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p38mapk  (Krishgen Biosystems)


Bioz Verified Symbol Krishgen Biosystems is a verified supplier
Bioz Manufacturer Symbol Krishgen Biosystems manufactures this product  
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    Structured Review

    Krishgen Biosystems p38mapk
    P38mapk, supplied by Krishgen Biosystems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/p38mapk/product/Krishgen Biosystems
    Average 94 stars, based on 1 article reviews
    p38mapk - by Bioz Stars, 2026-02
    94/100 stars

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    XBP suppressed renal AQP2 expression via <t>promoting</t> <t>CaSR/p38-MAPK-mediated</t> AQP2 ubiquitination and regulating CaSR/CREB-mediated AQP2 translation. (A and B) The protein expression of <t>p-p38MAPK/p38MAPK</t> in renal tissue from CHF rats (n = 6). (C and D) The protein expression of p-S261 AQP2 in renal tissue from CHF rats (n = 6). (E and F) The ubiquitination of AQP2 in renal tissue from CHF rats (n = 3). (G and H) The protein expression of p-CREB/CREB in renal tissue from CHF rats (n = 6). One-way nested ANOVA followed Dunnett's T3 test was used for multiple groups comparisons (B), and One-way nested ANOVA followed LSD test was used for multiple groups comparisons (D, F, H), the data are presented as Mean ± SEM, sham vs. model group, # p < 0.05, ## p < 0.01, ### p < 0.001; XBP(L/M/H) or QLQX vs. model group, * p < 0.05, ** p < 0.01, *** p < 0.001.
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    XBP suppressed renal AQP2 expression via promoting CaSR/p38-MAPK-mediated AQP2 ubiquitination and regulating CaSR/CREB-mediated AQP2 translation. (A and B) The protein expression of p-p38MAPK/p38MAPK in renal tissue from CHF rats (n = 6). (C and D) The protein expression of p-S261 AQP2 in renal tissue from CHF rats (n = 6). (E and F) The ubiquitination of AQP2 in renal tissue from CHF rats (n = 3). (G and H) The protein expression of p-CREB/CREB in renal tissue from CHF rats (n = 6). One-way nested ANOVA followed Dunnett's T3 test was used for multiple groups comparisons (B), and One-way nested ANOVA followed LSD test was used for multiple groups comparisons (D, F, H), the data are presented as Mean ± SEM, sham vs. model group, # p < 0.05, ## p < 0.01, ### p < 0.001; XBP(L/M/H) or QLQX vs. model group, * p < 0.05, ** p < 0.01, *** p < 0.001.

    Journal: Journal of Traditional and Complementary Medicine

    Article Title: Xinbao pill attenuated water retention by regulating the CaSR/AQP2 pathway in LAD-induced chronic heart failure rats

    doi: 10.1016/j.jtcme.2024.07.002

    Figure Lengend Snippet: XBP suppressed renal AQP2 expression via promoting CaSR/p38-MAPK-mediated AQP2 ubiquitination and regulating CaSR/CREB-mediated AQP2 translation. (A and B) The protein expression of p-p38MAPK/p38MAPK in renal tissue from CHF rats (n = 6). (C and D) The protein expression of p-S261 AQP2 in renal tissue from CHF rats (n = 6). (E and F) The ubiquitination of AQP2 in renal tissue from CHF rats (n = 3). (G and H) The protein expression of p-CREB/CREB in renal tissue from CHF rats (n = 6). One-way nested ANOVA followed Dunnett's T3 test was used for multiple groups comparisons (B), and One-way nested ANOVA followed LSD test was used for multiple groups comparisons (D, F, H), the data are presented as Mean ± SEM, sham vs. model group, # p < 0.05, ## p < 0.01, ### p < 0.001; XBP(L/M/H) or QLQX vs. model group, * p < 0.05, ** p < 0.01, *** p < 0.001.

    Article Snippet: Antibody against p38MAPK (#14064-1-AP) were bought from Proteintech Group, Inc (Chicago, USA).

    Techniques: Expressing, Ubiquitin Proteomics

    The underlying mechanism of XBP to improve water retention in CHF. XBP proved therapeutic effects against water retention in CHF through regulating CaSR/p38-MAPK-mediated AQP2 ubiquitination and CaSR/cAMP/CREB to inhibit AQP2 mRNA level.

    Journal: Journal of Traditional and Complementary Medicine

    Article Title: Xinbao pill attenuated water retention by regulating the CaSR/AQP2 pathway in LAD-induced chronic heart failure rats

    doi: 10.1016/j.jtcme.2024.07.002

    Figure Lengend Snippet: The underlying mechanism of XBP to improve water retention in CHF. XBP proved therapeutic effects against water retention in CHF through regulating CaSR/p38-MAPK-mediated AQP2 ubiquitination and CaSR/cAMP/CREB to inhibit AQP2 mRNA level.

    Article Snippet: Antibody against p38MAPK (#14064-1-AP) were bought from Proteintech Group, Inc (Chicago, USA).

    Techniques: Ubiquitin Proteomics